Closed Loop Care

Beyond One-Size Fits All Medicine

Individuals are frequently prescribed medications at standard doses, yet responses to these drugs can vary significantly, leading to diverse therapeutic outcomes and, in some cases, intolerable side effects. Optimizing the treatment for one or more medications often involves dose adjustments, multiple physician consultations, and repeated laboratory testing. Individuals frequently do not adhere to their medication treatments, complicating outcomes even further.  This ‘trial-and-error’ approach to medication management can be time-consuming, frustrating, and costly, potentially resulting in complications such as emergency care, hospitalization, or a diminished quality of life.

Defining Adaptable Closed Loop Systems

Closed-loop systems represent a personalized medicine approach that integrates sensor-based monitoring, intelligent algorithms, and real-time feedback to adjust dosing and deliver tailored messaging to optimize patient outcomes. Clinical and adherence targets are adapted over time, guided by an individual’s unique response. Advances in artificial intelligence, machine learning, sensor technology, home-based lab tests, and smart communication devices are propelling the evolution of closed-loop systems, making these personalized platforms potentially more cost-effective and accessible to a broader population.

Transforming Treatment Through
Intelligent Precision Medicine

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Adaptive Tailoring

We develop intelligent personalized medicine solutions that tailor therapeutic treatments using adaptive closed-loop systems to optimize and adapt care.

Built on Proprietary Technologies

Our proprietary technologies enable personalized medicine through generative AI, multi-modal biomarkers, connected drug delivery systems, decision support, and precision dosing algorithms.

Advancing the Standard
of Care

Healthcare providers navigate the personalized treatment journey with the support of our company’s clinical decision support systems and real-world evidence.

Innovations Enabling Adaptive Treatment

Under development are closed loop systems that personalize treatments using the novel technologies below. Products in development are investigational products. FDA has not yet evaluated the safety or effectiveness of these products.

Connected Drug Delivery
Drug delivery devices administer various types of medications (oral, injections, inhalation, solutions, and infusion) at the precise prescribed time and exact dosage, with real-time adaptability.
Multi-modal Biomarkers
Our closed-loop systems use multi-modal biomarkers including voice, image, lab tests, and sensor-based measurement.
Personalized
Our intelligent personalized treatment approach requires a baseline multi-dimensional profile of a patient’s health conditions, preferences, and lifestyle choices.
Real-Time Coaching
Utilizing our proprietary coaching engine with Generative AI enables personalized adherence coaching and drug and disease customized educational context.
Precision Dosing
By combining multi-modal biomarkers with strict medication dosing, our intelligent dosing algorithms recommend the next dose.
Decision Support
Using real-world evidence, and digital biomarkers, our decision support system assists healthcare providers in making more informed decisions about their patient’s treatment.
Dosing Adjustments
Our unique real-time dosing adjustments can be transmitted to the drug delivery device to optimize safe and accurate dosing updates. 
Messaging Adjustments
Adaptive messaging and educational context to the individual’s response over time, through distributing reinforcement messaging at the right time to close the loop and improve outcomes.

Closing the Loop Between Home and Healthcare Facilities

Our closed-loop systems position the home as a healthcare hub, enabling cohesive, connected care delivery across the entire ecosystem. Receiving first-class healthcare at home empowers individuals to take a leading role in managing their diagnostics, evaluations, treatments, and health outcomes.

Our solutions go beyond simply unifying healthcare system data with patient-generated data from the home. We are actively researching and developing ways to “close the loop” between treatment and therapeutic response by integrating artificial intelligence, machine learning, and comprehensive data from facilities and the home.

Platform Technologies Set Us Apart

Our closed-loop systems are built on scalable, secure platforms that are customizable to a wide range of therapeutic areas and medications, including the optimization of multiple medications.

Designed for flexibility, these platforms can be tailored to meet the unique needs of various medical conditions, ensuring personalized treatment approaches.

By deploying military-grade cybersecurity practices, our systems provide a robust foundation for optimizing clinical and patient care across diverse healthcare applications, ensuring that patient and provider data remains secure and private.